Polyneuropathies and other disorders of the peripheral nervous system

DOID MESH PheWeb

G6_POLYNEU

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G60-G64, G63.0*B02.29

Cause of death: ICD-10 G60-G64, G63.0*B02.29

4838

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

4838

Check minimum number of events None

4838

Include endpoints

G6_HEREMOSEN

G6_REFSUM

G6_NEUROHERAT

G6_IPNEUROP

G6_HERIPOTHUN

G6_GUILBAR

G6_DRUGPOLY

G6_ALCOPOLY

G6_TOXICPOLY

G6_POLYOTHUNS

G6_PERIPHOTH

5062

G6_POLYNEU

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Polyneuropathies and other disorders of the peripheral nervous system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

4905

1950

2955

Unadjusted prevalence (%)

1.59

1.12

2.19

Mean age at first event (years)

59.87

57.65

61.34

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.77 [2.07, 3.71]	6.7e-12	774
15 years	0.01	1.63 [1.28, 2.07]	5.7e-5	338
5 years	0.00	3.05 [2.46, 3.78]	2.4e-24	245
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_POLYNEU – Polyneuropathies and other disorders of the peripheral nervous system
GWS hits: 1

Survival analyses between endpoints

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Plot

before Polyneuropathies and other disorders of the peripheral nervous system
after Polyneuropathies and other disorders of the peripheral nervous system

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Table

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Drugs most likely to be purchased after Polyneuropathies and other disorders of the peripheral nervous system

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