Guillain-Barre syndrome

G6_GUILBAR

Guillain-Barre syndrome: Guillain-BarrC) syndrome (GBS) is the term used to describe a spectrum of rare post-infectious neuropathies that usually occur in otherwise healthy patients. GBS is clinically heterogeneous and encompasses acute inflammatory demyelinating polyradiculoneuropathy (AIDP), acute motor axonal neuropathy (AMAN) and acute motor-sensory axonal neuropathy (AMSAN), Miller-Fisher syndrome (MFS; see these terms) and some other regional variants.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G61.0

Hospital discharge: ICD-9 3570

Hospital discharge: ICD-8 35401

Cause of death: ICD-10 G61.0

Cause of death: ICD-9 3570

Cause of death: ICD-8 35401

1135

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

344

Check minimum number of events None

344

Include endpoints None

344

G6_GUILBAR

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 G61

Name in latin Syndroma Guillain-Barré

Similar endpoints

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List of similar endpoints to Guillain-Barre syndrome based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	329	153	176
Unadjusted prevalence (%)	0.11	0.09	0.13
Mean age at first event (years)	48.12	45.35	50.54

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_GUILBAR – Guillain-Barre syndrome
GWS hits: 0

Survival analyses between endpoints

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Plot

before Guillain-Barre syndrome
after Guillain-Barre syndrome

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Table

Loading survival analyses table

Drugs most likely to be purchased after Guillain-Barre syndrome

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