Demyelenating diseases of the central nervous system

G6_DEMYEL

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

2106

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G6_DEMYEL

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Demyelenating diseases of the central nervous system based on the number of shared cases.

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Summary Statistics

Key figures

All Female Male
Number of individuals 2012 1488 524
Unadjusted prevalence (%) 0.65 0.86 0.39
Mean age at first event (years) 40.04 38.75 43.72

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.33 [1.45, 3.73] 4.7e-4 96
15 years 0.01 1.46 [0.91, 2.34] 1.2e-1 39
5 years 0.00 3.75 [2.37, 5.93] 1.7e-8 27
1 year 0.00 10.25 [5.55, 18.95] 1.1e-13 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_DEMYEL – Demyelenating diseases of the central nervous system
GWS hits: 2

Survival analyses between endpoints

Plot

before Demyelenating diseases of the central nervous system
after Demyelenating diseases of the central nervous system

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Drugs most likely to be purchased after Demyelenating diseases of the central nervous system