Demyelenating diseases of the central nervous system

DOID MESH PheWeb

G6_DEMYEL

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

G6_MS

G6_DISSOTH

G6_OTHDEMYEL

2106

G6_DEMYEL

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Demyelenating diseases of the central nervous system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2012	1488	524
Unadjusted prevalence (%)	0.65	0.86	0.39
Mean age at first event (years)	40.04	38.75	43.72

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.33 [1.45, 3.73]	4.7e-4	96
15 years	0.01	1.46 [0.91, 2.34]	1.2e-1	39
5 years	0.00	3.75 [2.37, 5.93]	1.7e-8	27
1 year	0.00	10.25 [5.55, 18.95]	1.1e-13	14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_DEMYEL – Demyelenating diseases of the central nervous system
GWS hits: 2

Survival analyses between endpoints

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Plot

before Demyelenating diseases of the central nervous system
after Demyelenating diseases of the central nervous system

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Table

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Drugs most likely to be purchased after Demyelenating diseases of the central nervous system

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