Sleep apnoea

G6_SLEEPAPNO

sleep apnea: A disorder characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G47.3

Hospital discharge: ICD-9 3472

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 G47.3

Cause of death: ICD-9 3472

Cause of death: ICD-8 $!$

27976

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

27976

Check minimum number of events None

27976

Include endpoints None

27976

G6_SLEEPAPNO

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 G47

Name in latin Apnoea intrasomnalis

Similar endpoints

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List of similar endpoints to Sleep apnoea based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	27207	10578	16629
Unadjusted prevalence (%)	8.82	6.10	12.32
Mean age at first event (years)	55.74	56.18	55.47

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.22 [0.98, 1.52]	7.0e-2	1326
15 years	0.01	0.84 [0.69, 1.01]	6.4e-2	610
5 years	0.00	1.77 [1.49, 2.10]	5.4e-11	364
1 year	0.00	3.23 [2.57, 4.06]	5.2e-24	127

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_SLEEPAPNO – Sleep apnoea
GWS hits: 8

Survival analyses between endpoints

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Plot

before Sleep apnoea
after Sleep apnoea

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Table

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Drugs most likely to be purchased after Sleep apnoea

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