Systemic atrophies primarly affecting the central nervous system

G6_NEUATR

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 G10-G13
Cause of death: ICD-10 G10-G13

719

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

719

diagram downward connector

Check minimum number of events None

719

diagram downward connector
G6_NEUATR

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Systemic atrophies primarly affecting the central nervous system based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 830 347 483
Unadjusted prevalence (%) 0.27 0.20 0.36
Mean age at first event (years) 57.30 54.31 59.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 7.44 [5.35, 10.34] 8.2e-33 241
15 years 0.02 2.44 [1.74, 3.43] 2.7e-7 66
5 years 0.01 7.40 [5.00, 10.95] 1.4e-23 74
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_NEUATR – Systemic atrophies primarly affecting the central nervous system
GWS hits: 5

Survival analyses between endpoints

Plot

before Systemic atrophies primarly affecting the central nervous system
after Systemic atrophies primarly affecting the central nervous system

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Systemic atrophies primarly affecting the central nervous system