Inflammatory diseases of the central nervous system

DOID EFO MESH SNOMED PheWeb

G6_NEUINFL

encephalomyelitis: Inflammation of the brain and the spinal cord.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G00-G09

Cause of death: ICD-10 G00-G09

1274

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1274

Check minimum number of events None

1274

Include endpoints

G6_MENINGBACT

G6_MENINGVIR

G6_MENINGOTH

G6_ADEM

G6_ENCEPHBACT

G6_ENCEPHOTH

G6_CNSABSC

G6_CNSPHLEB

G6_NEUROINFSEQ

1964

G6_NEUINFL

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Inflammatory diseases of the central nervous system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1891	1044	847
Unadjusted prevalence (%)	0.61	0.60	0.63
Mean age at first event (years)	40.31	38.48	42.57

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.78 [3.21, 7.13]	1.6e-14	213
15 years	0.01	2.05 [1.45, 2.89]	5.1e-5	65
5 years	0.00	4.52 [3.13, 6.52]	7.2e-16	57
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_NEUINFL – Inflammatory diseases of the central nervous system
GWS hits: 0

Survival analyses between endpoints

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Plot

before Inflammatory diseases of the central nervous system
after Inflammatory diseases of the central nervous system

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Drugs most likely to be purchased after Inflammatory diseases of the central nervous system

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