Acute disseminated encephalitis/encephalomyelitis

G6_ADEM

acute disseminated encephalomyelitis: An encephalomyelitis characterized by inflammation located_in brain and located_in spinal cord that damages myelin. It usually occurs after viral infection, but also following vaccination, bacterial or parasitic infection.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G04.0#

Hospital discharge: ICD-9 3235A

Hospital discharge: ICD-8 32300

Cause of death: ICD-10 G04.0#

Cause of death: ICD-9 3235A

Cause of death: ICD-8 32300

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

G6_ADEM

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 G04

Name in latin Encephalitis disseminata acuta

Similar endpoints

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List of similar endpoints to Acute disseminated encephalitis/encephalomyelitis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

Unadjusted prevalence (%)

0.01

0.02

0.01

Mean age at first event (years)

26.96

25.07

29.95

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Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_ADEM – Acute disseminated encephalitis/encephalomyelitis
GWS hits:

Survival analyses between endpoints

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Plot

before Acute disseminated encephalitis/encephalomyelitis
after Acute disseminated encephalitis/encephalomyelitis

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Table

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Drugs most likely to be purchased after Acute disseminated encephalitis/encephalomyelitis

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