Diabetes, kidney failure

PheWeb

DM_KIDNEYFAIL

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E10.2+, E10.2+N08.39, E11.2+, E11.2+N08.39, E12.2+, E13.2+, E14.2+

Hospital discharge: ICD-9 2503

Hospital discharge: ICD-8 25002

Hospital discharge: excluded ICD-10 E12.2+

Cause of death: ICD-10 E10.2+, E10.2+N08.39, E11.2+, E11.2+N08.39, E12.2+, E13.2+, E14.2+

Cause of death: ICD-9 2503

Cause of death: ICD-8 25002

Cause of death: excluded ICD-10 E12.2+

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

3302

DM_KIDNEYFAIL

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diabetes, kidney failure based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3206	1160	2046
Unadjusted prevalence (%)	1.04	0.67	1.52
Mean age at first event (years)	54.07	48.89	57.01

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.13	11.54 [9.18, 14.50]	1.4e-97	868
15 years	0.03	4.36 [3.43, 5.54]	1.5e-33	288
5 years	0.01	9.17 [7.40, 11.36]	2.4e-91	294
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_KIDNEYFAIL – Diabetes, kidney failure
GWS hits:

Survival analyses between endpoints

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Plot

before Diabetes, kidney failure
after Diabetes, kidney failure

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Table

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Drugs most likely to be purchased after Diabetes, kidney failure

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