Osteopathies and chondropathies


secondary hypertrophic osteoarthropathy: Symmetrical osteitis of the four limbs, chiefly localized to the phalanges and the terminal epiphyses of the long bones of the forearm and leg, sometimes extending to the proximal ends of the limbs and the flat bones, and accompanied by dorsal kyphosis and joint involvement. It is often secondary to chronic conditions of the lungs and heart. (Dorland, 27th ed)

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 M80-M94, M90.6*C40.99, M90.6*C41.99
Cause of death: ICD-10 M80-M94, M90.6*C40.99, M90.6*C41.99


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


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Check minimum number of events None


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Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 14361 9070 5291
Unadjusted prevalence (%) 4.65 5.23 3.92
Mean age at first event (years) 52.38 54.37 48.96


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.21 [2.64, 3.91] 1.9e-31 1628
15 years 0.01 1.44 [1.20, 1.73] 9.5e-5 532
5 years 0.01 4.43 [3.77, 5.19] 5.9e-75 603
1 year 0.00 11.59 [9.73, 13.80] <1e-100 346

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: M13_OSTEOCHONDRO – Osteopathies and chondropathies
GWS hits: 0

Survival analyses between endpoints


before Osteopathies and chondropathies
after Osteopathies and chondropathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Osteopathies and chondropathies