Disorders of continuity of bone

MESH PheWeb

M13_BONECONTINUITY

No definition available.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M84

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 M84

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

1829

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1829

Check minimum number of events None

1829

Include endpoints None

1829

M13_BONECONTINUITY

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M80-M85

Name in latin Perturbationes continuitatis ossis

Similar endpoints

↥

List of similar endpoints to Disorders of continuity of bone based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	1775	1111	664
Unadjusted prevalence (%)	0.58	0.64	0.49
Mean age at first event (years)	50.98	51.95	49.35

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	5.96 [3.65, 9.72]	8.7e-13	115
15 years	0.02	2.62 [1.69, 4.08]	1.9e-5	42
5 years	0.01	5.21 [3.47, 7.81]	1.6e-15	32
1 year	0.00	21.76 [13.49, 35.09]	1.4e-36	31

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: M13_BONECONTINUITY – Disorders of continuity of bone
GWS hits: 0

Survival analyses between endpoints

↥

Plot

before Disorders of continuity of bone
after Disorders of continuity of bone

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Disorders of continuity of bone

↥