Paget disease


osteitis deformans: A disease of bone that initially results in the excessive resorption of bone (by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 M88
Hospital discharge: ICD-9 7310
Hospital discharge: ICD-8 72199
Cause of death: ICD-10 M88
Cause of death: ICD-9 7310
Cause of death: ICD-8 72199


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M86-M90
Name in latin Osteitis deformans Paget

Summary Statistics

Key figures

All Female Male
Number of individuals 87 41 46
Unadjusted prevalence (%) 0.03 0.02 0.03
Mean age at first event (years) 63.16 62.34 63.89


Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: M13_PAGET – Paget disease
GWS hits:

Survival analyses between endpoints


before Paget disease
after Paget disease

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