Otherdisorders of bone


secondary hypertrophic osteoarthropathy: Symmetrical osteitis of the four limbs, chiefly localized to the phalanges and the terminal epiphyses of the long bones of the forearm and leg, sometimes extending to the proximal ends of the limbs and the flat bones, and accompanied by dorsal kyphosis and joint involvement. It is often secondary to chronic conditions of the lungs and heart. (Dorland, 27th ed)

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 M89, M90*, M90.6*C40.99, M90.6*C41.99, M91-M94
Cause of death: ICD-10 M89, M90*, M90.6*C40.99, M90.6*C41.99, M91-M94


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


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Check minimum number of events None


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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Otherdisorders of bone based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 5079 2946 2133
Unadjusted prevalence (%) 1.65 1.70 1.58
Mean age at first event (years) 38.71 40.05 36.85


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.46 [0.96, 2.24] 7.8e-2 286
15 years 0.01 0.86 [0.59, 1.25] 4.2e-1 104
5 years 0.00 2.02 [1.42, 2.86] 8.9e-5 60
1 year 0.00 7.68 [5.30, 11.14] 6.0e-27 44

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: M13_OTHERBONE – Otherdisorders of bone
GWS hits: 0

Survival analyses between endpoints


before Otherdisorders of bone
after Otherdisorders of bone

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Drugs most likely to be purchased after Otherdisorders of bone