Other specified/unspecified disorders of bone/cartilage

M13_BONEDISNAS

cartilage disease: Softening and degeneration of the CARTILAGE. Pathological processes involving the chondral tissue (CARTILAGE).

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M89.80, M89.81, M89.88, M89.9, M94.8, M94.9

Hospital discharge: ICD-9 7339

Hospital discharge: ICD-8 7239[8-9]

Cause of death: ICD-10 M89.80, M89.81, M89.88, M89.9, M94.8, M94.9

Cause of death: ICD-9 7339

Cause of death: ICD-8 7239[8-9]

1650

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

634

Check minimum number of events None

634

Include endpoints None

634

M13_BONEDISNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other specified/unspecified disorders of bone/cartilage based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	622	271	351
Unadjusted prevalence (%)	0.20	0.16	0.26
Mean age at first event (years)	36.00	40.53	32.51

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.81 [0.85, 3.84]	1.2e-1	50
15 years	0.01	0.98 [0.49, 1.99]	9.7e-1	17
5 years	0.00	2.26 [1.10, 4.61]	2.6e-2	10
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_BONEDISNAS – Other specified/unspecified disorders of bone/cartilage
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other specified/unspecified disorders of bone/cartilage
after Other specified/unspecified disorders of bone/cartilage

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Table

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Drugs most likely to be purchased after Other specified/unspecified disorders of bone/cartilage

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