Alogoneurodystrophy

M13_ALGONEURO

reflex sympathetic dystrophy: Complex regional pain syndrome type 1 (CRPS1) is a form of complex regional pain syndrome (see this term) in which the pain is disproportionate to any known inciting event and is characterized by continuous pain, allodynia, or hyperalgesia as well as edema, coloration (changes in skin blood flow), or abnormal sudomotor activity in the region of pain. Onset of CRPS1 symptoms may occur within a few days to a month after an injury or trauma to the affected limb.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M89.0

Hospital discharge: ICD-9 7337

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 M89.0

Cause of death: ICD-9 7337

Cause of death: ICD-8 $!$

703

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

703

Check minimum number of events None

703

Include endpoints None

703

M13_ALGONEURO

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M89

Name in latin Algoneurodystrophia

Similar endpoints

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List of similar endpoints to Alogoneurodystrophy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	671	511	160
Unadjusted prevalence (%)	0.22	0.29	0.12
Mean age at first event (years)	47.25	46.48	49.72

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.89 [1.01, 8.23]	4.7e-2	29
15 years	0.01	1.47 [0.49, 4.38]	4.9e-1	14
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_ALGONEURO – Alogoneurodystrophy
GWS hits: 0

Survival analyses between endpoints

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Plot

before Alogoneurodystrophy
after Alogoneurodystrophy

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Alogoneurodystrophy

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