Any dementia

KRA_PSY_DEMENTIA

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 F00-F09, F05.1, G30
Hospital discharge: ICD-9  290|2912A|2828C|2941A|3310A|3311A|4378A 
Hospital discharge: ICD-8 290
Cause of death: ICD-10 F00-F09, F05.1, G30
Cause of death: ICD-9  290|2912A|2828C|2941A|3310A|3311A|4378A 
Cause of death: ICD-8 290

10118

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

10084

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Check minimum number of events None

10084

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Include endpoints None

10084

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KRA_PSY_DEMENTIA

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 9722 4281 5441
Unadjusted prevalence (%) 3.15 2.47 4.03
Mean age at first event (years) 77.53 77.94 77.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.13 9.65 [8.54, 10.90] <1e-100 5130
15 years 0.02 2.77 [2.46, 3.11] 3.6e-65 1192
5 years 0.01 7.13 [6.46, 7.88] <1e-100 2228
1 year 0.00 17.79 [15.91, 19.89] <1e-100 1686

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: KRA_PSY_DEMENTIA – Any dementia
GWS hits: 2

Survival analyses between endpoints

Plot

before Any dementia
after Any dementia

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