Noninfective enteritis and colitis

K11_ENERCOLNONINF

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 K50-K52
Cause of death: ICD-10 K50-K52

12006

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

12006

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Check minimum number of events None

12006

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K11_ENERCOLNONINF

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 13146 7343 5803
Unadjusted prevalence (%) 4.26 4.23 4.30
Mean age at first event (years) 44.38 43.11 45.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.74 [1.37, 2.21] 5.9e-6 1230
15 years 0.01 1.02 [0.83, 1.24] 8.8e-1 475
5 years 0.00 2.30 [1.94, 2.72] 2.4e-22 322
1 year 0.00 7.92 [6.53, 9.60] 8.0e-99 222

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_ENERCOLNONINF – Noninfective enteritis and colitis
GWS hits: 11

Survival analyses between endpoints

Plot

before Noninfective enteritis and colitis
after Noninfective enteritis and colitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Noninfective enteritis and colitis