Inflammatory bowel disease

K11_IBD

inflammatory bowel disease: A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

8966

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K11_IBD

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Inflammatory bowel disease based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 8704 4644 4060
Unadjusted prevalence (%) 2.82 2.68 3.01
Mean age at first event (years) 41.87 40.13 43.87

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.86 [1.49, 2.31] 2.5e-8 574
15 years 0.01 1.11 [0.90, 1.39] 3.3e-1 238
5 years 0.00 2.27 [1.77, 2.90] 9.1e-11 138
1 year 0.00 5.78 [4.27, 7.82] 5.8e-30 67

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_IBD – Inflammatory bowel disease
GWS hits: 19

Survival analyses between endpoints

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Plot

before Inflammatory bowel disease
after Inflammatory bowel disease

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Drugs most likely to be purchased after Inflammatory bowel disease

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