IBD patients in KELA-register

K11_KELAIBD

inflammatory bowel disease: A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

KELA reimbursements: KELA codes 208|209

6136

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Check pre-conditions, main-only, mode, ICD version None

6136

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Check minimum number of events None

6136

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Include endpoints None

6136

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K11_KELAIBD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3

Similar endpoints

List of similar endpoints to IBD patients in KELA-register based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 5963 3165 2798
Unadjusted prevalence (%) 1.93 1.82 2.07
Mean age at first event (years) 40.28 38.45 42.36

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.73 [0.45, 1.19] 2.1e-1 185
15 years 0.00 0.54 [0.34, 0.86] 8.7e-3 82
5 years 0.00 0.87 [0.52, 1.45] 5.8e-1 27
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_KELAIBD – IBD patients in KELA-register
GWS hits: 22

Survival analyses between endpoints

Plot

before IBD patients in KELA-register
after IBD patients in KELA-register

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Drugs most likely to be purchased after IBD patients in KELA-register