Ulcerative colitis (strict definition, all Crohn cases excluded)

PheWeb

K11_UC_NOCD

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions

K11_KELAIBD

and not K11_CROHN

3809

Filter registries

Hospital Discharge: ICD-10 K51

Hospital discharge: ICD-9 556

Hospital discharge: ICD-8 5631|569

Hospital discharge: excluded ICD-9 5564A

Cause of death: ICD-10 K51

Cause of death: ICD-9 556

Cause of death: ICD-8 5631|569

Cause of death: excluded ICD-9 5564A

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

3509

K11_UC_NOCD

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF3

Parent code in ICD-10 K50-K52

Name in latin Colitis ulcerosa

Similar endpoints

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List of similar endpoints to Ulcerative colitis (strict definition, all Crohn cases excluded) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3407	1762	1645
Unadjusted prevalence (%)	1.10	1.02	1.22
Mean age at first event (years)	41.25	39.00	43.65

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.34 [0.85, 2.12]	2.1e-1	118
15 years	0.01	0.98 [0.57, 1.69]	9.4e-1	61
5 years	0.00	0.95 [0.47, 1.91]	8.8e-1	14
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_UC_NOCD – Ulcerative colitis (strict definition, all Crohn cases excluded)
GWS hits: 13

Survival analyses between endpoints

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Plot

before Ulcerative colitis (strict definition, all Crohn cases excluded)
after Ulcerative colitis (strict definition, all Crohn cases excluded)

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Table

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Drugs most likely to be purchased after Ulcerative colitis (strict definition, all Crohn cases excluded)

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