Hypotyreosis and Thyroxin purchase for inclusion criteria

PheWeb

HYPOT_THYRO_INCL

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E03

Cause of death: ICD-10 E03

12010

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

12005

Check minimum number of events None

12005

Include endpoints

HYPOTHYROIDISM

39877

HYPOT_THYRO_INCL

Extra metadata

First used in FinnGen datafreeze DF7

Similar endpoints

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List of similar endpoints to Hypotyreosis and Thyroxin purchase for inclusion criteria based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	38626	30946	7680
Unadjusted prevalence (%)	12.52	17.83	5.69
Mean age at first event (years)	52.04	50.52	58.15

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.35 [1.18, 1.55]	1.9e-5	2432
15 years	0.01	0.95 [0.84, 1.08]	4.4e-1	1219
5 years	0.00	1.71 [1.50, 1.95]	1.9e-15	629
1 year	0.00	1.73 [1.39, 2.16]	8.7e-7	117

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: HYPOT_THYRO_INCL – Hypotyreosis and Thyroxin purchase for inclusion criteria
GWS hits:

Survival analyses between endpoints

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Plot

before Hypotyreosis and Thyroxin purchase for inclusion criteria
after Hypotyreosis and Thyroxin purchase for inclusion criteria

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Table

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Drugs most likely to be purchased after Hypotyreosis and Thyroxin purchase for inclusion criteria

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