Syndrome of inappropriate secretion of antidiuretic hormone

E4_ANTIDIU

inappropriate ADH syndrome: A syndrome characterized by abnormal secretion of antidiuretic hormone in conjunction with neoplastic growth occurring anywhere in the body.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E22.2

Hospital discharge: ICD-9 2536X

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E22.2

Cause of death: ICD-9 2536X

Cause of death: ICD-8 $!$

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Include endpoints None

E4_ANTIDIU

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E22

Name in latin Syndroma secretionis impropriae hormonis antidiuretici

Similar endpoints

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List of similar endpoints to Syndrome of inappropriate secretion of antidiuretic hormone based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	83	42	41
Unadjusted prevalence (%)	0.03	0.02	0.03
Mean age at first event (years)	66.22	65.99	66.46

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ANTIDIU – Syndrome of inappropriate secretion of antidiuretic hormone
GWS hits:

Survival analyses between endpoints

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Plot

before Syndrome of inappropriate secretion of antidiuretic hormone
after Syndrome of inappropriate secretion of antidiuretic hormone

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Table

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Drugs most likely to be purchased after Syndrome of inappropriate secretion of antidiuretic hormone

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