Syndrome of inappropriate secretion of antidiuretic hormone

E4_ANTIDIU

inappropriate ADH syndrome: A syndrome characterized by abnormal secretion of antidiuretic hormone in conjunction with neoplastic growth occurring anywhere in the body.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 E22.2
Hospital discharge: ICD-9 2536X
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E22.2
Cause of death: ICD-9 2536X
Cause of death: ICD-8 $!$

84

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

84

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Check minimum number of events None

84

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Include endpoints None

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E4_ANTIDIU

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E22
Name in latin Syndroma secretionis impropriae hormonis antidiuretici

Summary Statistics

Key figures

All Female Male
Number of individuals 83 42 41
Unadjusted prevalence (%) 0.03 0.02 0.03
Mean age at first event (years) 66.22 65.99 66.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_ANTIDIU – Syndrome of inappropriate secretion of antidiuretic hormone
GWS hits:

Survival analyses between endpoints

Plot

before Syndrome of inappropriate secretion of antidiuretic hormone
after Syndrome of inappropriate secretion of antidiuretic hormone

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Drugs most likely to be purchased after Syndrome of inappropriate secretion of antidiuretic hormone