Exclusions for E4_PCOS_BROAD

E4_PCOS_BROAD_EXCLUSIONS

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 C74, D35.2&, E22, E23, E24, E25, E27, Q96
Hospital discharge: ICD-9 2273|253|255|6116|2270|194
Hospital discharge: ICD-8 2262|253|255|258|2260
Cause of death: ICD-10 C74, D35.2&, E22, E23, E24, E25, E27, Q96
Cause of death: ICD-9 2273|253|255|6116|2270|194
Cause of death: ICD-8 2262|253|255|258|2260

4482

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

4145

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Check minimum number of events None

4145

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Include endpoints None

4145

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E4_PCOS_BROAD_EXCLUSIONS

Extra metadata

First used in FinnGen datafreeze DF6v3

Summary Statistics

Key figures

All Female Male
Number of individuals 3998 2437 1561
Unadjusted prevalence (%) 1.30 1.40 1.16
Mean age at first event (years) 43.92 41.23 48.11

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.28 [1.32, 3.94] 3.0e-3 299
15 years 0.01 1.27 [0.81, 2.00] 2.9e-1 108
5 years 0.00 2.60 [1.72, 3.93] 5.2e-6 73
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_PCOS_BROAD_EXCLUSIONS – Exclusions for E4_PCOS_BROAD
GWS hits:

Survival analyses between endpoints

Plot

before Exclusions for E4_PCOS_BROAD
after Exclusions for E4_PCOS_BROAD

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Drugs most likely to be purchased after Exclusions for E4_PCOS_BROAD