Hyperprolactinaemia

E4_HYPERPRO

hyperprolactinemia: An acquired metabolic disease that has_material_basis_in the presence of abnormally-high levels of prolactin in the blood.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 E22.1#
Hospital discharge: ICD-9 2531A
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E22.1#
Cause of death: ICD-9 2531A
Cause of death: ICD-8 $!$

850

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

850

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Check minimum number of events None

850

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Include endpoints None

850

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E4_HYPERPRO

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E22
Name in latin Hyperprolactinaemia

Summary Statistics

Key figures

All Female Male
Number of individuals 818 683 135
Unadjusted prevalence (%) 0.27 0.39 0.10
Mean age at first event (years) 38.25 35.92 50.06

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 1.08 [0.38, 3.02] 8.9e-1 19
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_HYPERPRO – Hyperprolactinaemia
GWS hits: 0

Survival analyses between endpoints

Plot

before Hyperprolactinaemia
after Hyperprolactinaemia

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Drugs most likely to be purchased after Hyperprolactinaemia