Hyperprolactinaemia

E4_HYPERPRO

hyperprolactinemia: An acquired metabolic disease that has_material_basis_in the presence of abnormally-high levels of prolactin in the blood.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E22.1#

Hospital discharge: ICD-9 2531A

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E22.1#

Cause of death: ICD-9 2531A

Cause of death: ICD-8 $!$

850

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

850

Check minimum number of events None

850

Include endpoints None

850

E4_HYPERPRO

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E22

Name in latin Hyperprolactinaemia

Similar endpoints

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List of similar endpoints to Hyperprolactinaemia based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Hyperprolactinaemia, drug-induced

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	818	683	135
Unadjusted prevalence (%)	0.27	0.39	0.10
Mean age at first event (years)	38.25	35.92	50.06

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	1.08 [0.38, 3.02]	8.9e-1	19
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_HYPERPRO – Hyperprolactinaemia
GWS hits: 0

Survival analyses between endpoints

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Plot

before Hyperprolactinaemia
after Hyperprolactinaemia

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Hyperprolactinaemia

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