Drug-induced adrenocortical insufficiency

PheWeb

DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E27.3#

282

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10

282

Check minimum number of events None

282

Include endpoints None

282

DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF5

Similar endpoints

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List of similar endpoints to Drug-induced adrenocortical insufficiency based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	275	191	84
Unadjusted prevalence (%)	0.09	0.11	0.06
Mean age at first event (years)	54.81	53.40	58.02

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY – Drug-induced adrenocortical insufficiency
GWS hits: 1

Survival analyses between endpoints

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Plot

before Drug-induced adrenocortical insufficiency
after Drug-induced adrenocortical insufficiency

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Table

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Drugs most likely to be purchased after Drug-induced adrenocortical insufficiency

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