Extrapyramidal and movement disorders

G6_XTRAPYR

basal ganglia disease: A disease involving the basal ganglia.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 G20-G26
Cause of death: ICD-10 G20-G26

7093

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

7093

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Check minimum number of events None

7093

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G6_XTRAPYR

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 7229 3704 3525
Unadjusted prevalence (%) 2.34 2.13 2.61
Mean age at first event (years) 60.68 58.46 63.01

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.39 [2.59, 4.45] 1.2e-18 1207
15 years 0.01 2.11 [1.73, 2.58] 3.4e-13 603
5 years 0.00 3.40 [2.90, 4.00] 1.5e-50 386
1 year 0.00 5.43 [4.38, 6.75] 5.6e-53 129

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_XTRAPYR – Extrapyramidal and movement disorders
GWS hits: 0

Survival analyses between endpoints

Plot

before Extrapyramidal and movement disorders
after Extrapyramidal and movement disorders

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Drugs most likely to be purchased after Extrapyramidal and movement disorders