Pre-eclampsia superimposed on chronic hypertension

O15_PREECLAMPS_CHRONIC_HYPERT

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only females

180574

Check conditions None

180574

Filter registries

Hospital Discharge: ICD-10 O11

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 O11

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

123

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

123

Check minimum number of events None

123

Include endpoints None

123

O15_PREECLAMPS_CHRONIC_HYPERT

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF3

Parent code in ICD-10 O10-O16

Name in latin Hypertensio prae-existens cum proteinuria superposita

Similar endpoints

↥

List of similar endpoints to Pre-eclampsia superimposed on chronic hypertension based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	121	121	-
Unadjusted prevalence (%)	0.04	0.07	-
Mean age at first event (years)	33.88	33.88	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: O15_PREECLAMPS_CHRONIC_HYPERT – Pre-eclampsia superimposed on chronic hypertension
GWS hits: 0

Survival analyses between endpoints

↥

Plot

before Pre-eclampsia superimposed on chronic hypertension
after Pre-eclampsia superimposed on chronic hypertension

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Pre-eclampsia superimposed on chronic hypertension

↥