Temporal arteritis


temporal arteritis: Giant cell arteritis (GCA) is a large vessel vasculitis predominantly involving the arteries originating from the aortic arch and especially the extracranial branches of the carotid arteries.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 M31.5
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M31.5
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 5
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Arteritis gigantocellularis cum polymyalgia reumatica

Summary Statistics

Key figures

All Female Male
Number of individuals 685 425 260
Unadjusted prevalence (%) 0.22 0.24 0.19
Mean age at first event (years) 68.29 67.61 69.41


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.85 [1.97, 7.54] 8.5e-5 96
15 years 0.01 1.82 [1.06, 3.12] 3.0e-2 38
5 years 0.00 4.34 [2.87, 6.57] 3.3e-12 38
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: M13_TEMPARTERIT – Temporal arteritis
GWS hits: 0

Survival analyses between endpoints


before Temporal arteritis
after Temporal arteritis

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Drugs most likely to be purchased after Temporal arteritis