Giant cell arteritis with polymyalgia rheumatica

GIANT_CELL_TEMP_ARTERITIS

polymyalgia rheumatica: Polymyalgia rheumatica is a common inflammatory condition that often affects people over the age of 50 years. Characteristic symptoms are shoulder and hip girdle pain and prolonged morning stiffness. Markers of inflammation are often elevated.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M31.5

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 M31.5

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

702

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

702

Check minimum number of events None

702

Include endpoints None

702

GIANT_CELL_TEMP_ARTERITIS

Extra metadata

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M31

Name in latin Arteritis gigantocellularis cum polymyalgia reumatica

Similar endpoints

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List of similar endpoints to Giant cell arteritis with polymyalgia rheumatica based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Temporal arteritis

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

685

425

260

Unadjusted prevalence (%)

0.22

0.24

0.19

Mean age at first event (years)

68.29

67.61

69.41

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.77 [1.22, 6.25]	1.4e-2	96
15 years	0.01	1.37 [0.66, 2.85]	4.0e-1	38
5 years	0.00	3.80 [2.34, 6.19]	7.3e-8	38
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: GIANT_CELL_TEMP_ARTERITIS – Giant cell arteritis with polymyalgia rheumatica
GWS hits: 0

Survival analyses between endpoints

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Plot

before Giant cell arteritis with polymyalgia rheumatica
after Giant cell arteritis with polymyalgia rheumatica

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Table

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Drugs most likely to be purchased after Giant cell arteritis with polymyalgia rheumatica

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