Deforming dorsopathies

M13_DEFORMDORSO

scoliosis: A congenital or acquired spinal deformity characterized by lateral curvature of the spine.

Endpoint definition

↥
FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 M40-M43
Cause of death: ICD-10 M40-M43

6844

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

6844

diagram downward connector

Check minimum number of events None

6844

diagram downward connector
M13_DEFORMDORSO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

↥

List of similar endpoints to Deforming dorsopathies based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 7333 4904 2429
Unadjusted prevalence (%) 2.38 2.83 1.80
Mean age at first event (years) 48.25 48.05 48.66

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.58 [1.13, 2.21] 6.9e-3 316
15 years 0.01 0.96 [0.68, 1.35] 8.0e-1 144
5 years 0.00 1.87 [1.30, 2.69] 7.1e-4 92
1 year 0.00 2.97 [1.87, 4.72] 3.9e-6 28

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: M13_DEFORMDORSO – Deforming dorsopathies
GWS hits: 0

Survival analyses between endpoints

↥

Plot

before Deforming dorsopathies
after Deforming dorsopathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Deforming dorsopathies

↥