Kyphosis

M13_KYPHOSIS

phimosis: A condition in which there is constriction in the tip of the foreskin resulting in inability to fully retract the foreskin over the glans penis. Causes include balanoposthitis, balanitis xerotica obliterans, and untreated diabetes.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M40.0, M40.1, M40.2
Hospital discharge: ICD-9 737[0-1]
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M40.0, M40.1, M40.2
Cause of death: ICD-9 737[0-1]
Cause of death: ICD-8 $!$

259

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

244

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Check minimum number of events None

244

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Include endpoints None

244

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M13_KYPHOSIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 236 143 93
Unadjusted prevalence (%) 0.08 0.08 0.07
Mean age at first event (years) 57.26 58.58 55.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_KYPHOSIS – Kyphosis
GWS hits: 0

Survival analyses between endpoints

Plot

before Kyphosis
after Kyphosis

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