Scoliosis

DOID EFO MESH SNOMED PheWeb

M13_SCOLIOSIS

scoliosis: A congenital or acquired spinal deformity characterized by lateral curvature of the spine.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M41

Hospital discharge: ICD-9 7373

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 M41

Cause of death: ICD-9 7373

Cause of death: ICD-8 $!$

1972

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1966

Check minimum number of events None

1966

Include endpoints None

1966

M13_SCOLIOSIS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M40-M43

Name in latin Scoliosis

Similar endpoints

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List of similar endpoints to Scoliosis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1893	1488	405
Unadjusted prevalence (%)	0.61	0.86	0.30
Mean age at first event (years)	40.69	40.64	40.87

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.57 [2.03, 6.27]	9.7e-6	53
15 years	0.01	1.20 [0.60, 2.39]	6.0e-1	16
5 years	0.00	4.22 [2.44, 7.32]	2.8e-7	25
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_SCOLIOSIS – Scoliosis
GWS hits: 0

Survival analyses between endpoints

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Plot

before Scoliosis
after Scoliosis

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Table

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Drugs most likely to be purchased after Scoliosis

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