Other disorders of skin and subcutaneous tissue

L12_OTHERSKINSUBCUTIS

skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L80-L99

Cause of death: ICD-10 L80-L99

16790

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

16790

Check minimum number of events None

16790

Include endpoints

L12_VITILIGO

L12_OTHPIGMENTATION

L12_SEBORRKERAT

L12_ACANTHNIGRICANS

L12_CORNSANDCALLOS

L12_EPIDERMALTHICKOTH

L12_ACQICTHY

L12_ACQKERAT

L12_KERATPUNCTATA

L12_XEROSCUT

L12_EPIDERMTHICKNAS

L12_KERATODERMAINOTH

L12_TRANSEPIDERMELIMINATION

L12_PYODERMAGANGRENOSUM

L12_DECUBITANSULCERANDPRESSURE

L12_ATROPHICSKIN

L12_LICHENSCLERATROPH

L12_ANETODERMA

L12_ATROPODERMAPASINI

L12_ACRODERMATITIS

L12_SCARCONDITIONS

L12_STRIAEATROPHICAE

L12_ATROPHICSKINNAS

L12_HYPERTROPHICSKIN

L12_GRANULOMATOUSSKIN

L12_LUPUS

L12_LOCALDCONNECTISSUEOTH

L12_VASCULITISSKIN

L12_ULCERLOWLIMB

L12_OTHERDISSKINANDSUBCUTIS

L12_SKININOTH

17834

L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other disorders of skin and subcutaneous tissue based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

17265

10319

6946

Unadjusted prevalence (%)

5.60

5.95

5.14

Mean age at first event (years)

56.41

54.55

59.19

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.98 [2.43, 3.66]	6.8e-26	2042
15 years	0.01	1.45 [1.22, 1.72]	2.2e-5	729
5 years	0.00	3.68 [3.20, 4.24]	3.2e-74	692
1 year	0.00	11.35 [9.67, 13.31]	<1e-100	456

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_OTHERSKINSUBCUTIS – Other disorders of skin and subcutaneous tissue
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other disorders of skin and subcutaneous tissue
after Other disorders of skin and subcutaneous tissue

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Table

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Drugs most likely to be purchased after Other disorders of skin and subcutaneous tissue

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