Other disorders of skin and subcutaneous tissue

L12_OTHERSKINSUBCUTIS

skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L80-L99

Cause of death: ICD-10 L80-L99

16790

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

16790

Check minimum number of events None

16790

Include endpoints

L12_VITILIGO

L12_OTHPIGMENTATION

L12_SEBORRKERAT

L12_ACANTHNIGRICANS

L12_CORNSANDCALLOS

L12_EPIDERMALTHICKOTH

L12_ACQICTHY

L12_ACQKERAT

L12_KERATPUNCTATA

L12_XEROSCUT

L12_EPIDERMTHICKNAS

L12_KERATODERMAINOTH

L12_TRANSEPIDERMELIMINATION

L12_PYODERMAGANGRENOSUM

L12_DECUBITANSULCERANDPRESSURE

L12_ATROPHICSKIN

L12_LICHENSCLERATROPH

L12_ANETODERMA

L12_ATROPODERMAPASINI

L12_ACRODERMATITIS

L12_SCARCONDITIONS

L12_STRIAEATROPHICAE

L12_ATROPHICSKINNAS

L12_HYPERTROPHICSKIN

L12_GRANULOMATOUSSKIN

L12_LUPUS

L12_LOCALDCONNECTISSUEOTH

L12_VASCULITISSKIN

L12_ULCERLOWLIMB

L12_OTHERDISSKINANDSUBCUTIS

L12_SKININOTH

17834

L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other disorders of skin and subcutaneous tissue based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	17265	10319	6946
Unadjusted prevalence (%)	5.60	5.95	5.14
Mean age at first event (years)	56.41	54.55	59.19

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.98 [2.43, 3.66]	6.8e-26	2042
15 years	0.01	1.45 [1.22, 1.72]	2.2e-5	729
5 years	0.00	3.68 [3.20, 4.24]	3.2e-74	692
1 year	0.00	11.35 [9.67, 13.31]	<1e-100	456

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_OTHERSKINSUBCUTIS – Other disorders of skin and subcutaneous tissue
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other disorders of skin and subcutaneous tissue
after Other disorders of skin and subcutaneous tissue

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Table

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Drugs most likely to be purchased after Other disorders of skin and subcutaneous tissue

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