Other and unspecified atrophic disorders of skin

L12_ATROPHICSKINNAS

skin atrophy: The structural changes and the signs and symptoms of chronologically aged skinand those of corticosteroid induced chronicatrophyof theskinare partially very similar.Thinningof epidermis and laxity as well as dryness, purpura and echymoses occur in both conditions.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L90.8, L90.9

Hospital discharge: ICD-9 7018X

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 L90.8, L90.9

Cause of death: ICD-9 7018X

Cause of death: ICD-8 $!$

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

L12_ATROPHICSKINNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified atrophic disorders of skin based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	75	64	11
Unadjusted prevalence (%)	0.02	0.04	0.01
Mean age at first event (years)	56.09	56.55	53.45

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_ATROPHICSKINNAS – Other and unspecified atrophic disorders of skin
GWS hits:

Survival analyses between endpoints

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Plot

before Other and unspecified atrophic disorders of skin
after Other and unspecified atrophic disorders of skin

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Table

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Drugs most likely to be purchased after Other and unspecified atrophic disorders of skin

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