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Atrophic disorders of skin

DOIDEFOMESHSNOMED PheWeb

L12_ATROPHICSKIN

skin atrophy: The structural changes and the signs and symptoms of chronologically aged skinand those of corticosteroid induced chronicatrophyof theskinare partially very similar.Thinningof epidermis and laxity as well as dryness, purpura and echymoses occur in both conditions.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 L90
Cause of death: ICD-10 L90

2504

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

2504

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Check minimum number of events None

2504

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Include endpoints

2673

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L12_ATROPHICSKIN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L80-L99
Name in latin Morbositates atrophicae cutis

Similar endpoints

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List of similar endpoints to Atrophic disorders of skin based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 2594 2122 472
Unadjusted prevalence (%) 0.84 1.22 0.35
Mean age at first event (years) 53.74 54.90 48.54

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.93 [0.54, 1.60] 7.9e-1 95
15 years 0.00 0.68 [0.41, 1.12] 1.3e-1 49
5 years 0.00 1.07 [0.64, 1.80] 7.9e-1 24
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_ATROPHICSKIN – Atrophic disorders of skin
GWS hits: 0

Survival analyses between endpoints

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Plot

before Atrophic disorders of skin
after Atrophic disorders of skin

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Drugs most likely to be purchased after Atrophic disorders of skin

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