Pyoderma gangrenosum

L12_PYODERMAGANGRENOSUM

pyoderma gangrenosum: ['An idiopathic, rapidly evolving, and severely debilitating disease occurring most commonly in association with chronic ulcerative colitis. It is characterized by the presence of boggy, purplish ulcers with undermined borders, appearing mostly on the legs. The majority of cases are in people between 40 and 60 years old. Its etiology is unknown.']

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L88

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 L88

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

115

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

115

Check minimum number of events None

115

Include endpoints None

115

L12_PYODERMAGANGRENOSUM

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L80-L99

Name in latin Pyoderma gangraenosum

Similar endpoints

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List of similar endpoints to Pyoderma gangrenosum based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Pyoderma gangrenosum

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	108	66	42
Unadjusted prevalence (%)	0.04	0.04	0.03
Mean age at first event (years)	52.47	49.99	56.38

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_PYODERMAGANGRENOSUM – Pyoderma gangrenosum
GWS hits: 0

Survival analyses between endpoints

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Plot

before Pyoderma gangrenosum
after Pyoderma gangrenosum

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Table

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Drugs most likely to be purchased after Pyoderma gangrenosum

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