Acanthosis nigricans

L12_ACANTHNIGRICANS

acanthosis nigricans: a brown to black, poorly defined, velvety hyperpigmentation of the skin. It is usually found in body folds, such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead, and other areas.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L83

Hospital discharge: ICD-9 7012A

Hospital discharge: ICD-8 7011

Cause of death: ICD-10 L83

Cause of death: ICD-9 7012A

Cause of death: ICD-8 7011

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

L12_ACANTHNIGRICANS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L80-L99

Name in latin Acanthosis nigricans

Similar endpoints

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List of similar endpoints to Acanthosis nigricans based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	79	43	36
Unadjusted prevalence (%)	0.03	0.02	0.03
Mean age at first event (years)	35.16	38.86	30.74

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_ACANTHNIGRICANS – Acanthosis nigricans
GWS hits:

Survival analyses between endpoints

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Plot

before Acanthosis nigricans
after Acanthosis nigricans

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Table

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Drugs most likely to be purchased after Acanthosis nigricans

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