Acanthosis nigricans

L12_ACANTHNIGRICANS

acanthosis nigricans: a brown to black, poorly defined, velvety hyperpigmentation of the skin. It is usually found in body folds, such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead, and other areas.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 L83
Hospital discharge: ICD-9 7012A
Hospital discharge: ICD-8 7011
Cause of death: ICD-10 L83
Cause of death: ICD-9 7012A
Cause of death: ICD-8 7011

90

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

83

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Check minimum number of events None

83

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Include endpoints None

83

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L12_ACANTHNIGRICANS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L80-L99
Name in latin Acanthosis nigricans

Summary Statistics

Key figures

All Female Male
Number of individuals 79 43 36
Unadjusted prevalence (%) 0.03 0.02 0.03
Mean age at first event (years) 35.16 38.86 30.74

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_ACANTHNIGRICANS – Acanthosis nigricans
GWS hits:

Survival analyses between endpoints

Plot

before Acanthosis nigricans
after Acanthosis nigricans

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Drugs most likely to be purchased after Acanthosis nigricans