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Disorders of gallbladder, biliary tract and pancreas

DOIDEFOMESHSNOMED PheWeb

K11_GALLBILPANC

biliary tract disease: A disease involving the biliary tree.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 K80-K87
Cause of death: ICD-10 K80-K87

27111

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

27111

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Check minimum number of events None

27111

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Include endpoints

36899

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K11_GALLBILPANC

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 35712 22618 13094
Unadjusted prevalence (%) 11.57 13.03 9.70
Mean age at first event (years) 51.71 48.66 56.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.68 [1.50, 1.88] 1.5e-19 4900
15 years 0.01 1.03 [0.93, 1.14] 5.2e-1 2041
5 years 0.00 1.88 [1.70, 2.07] 6.6e-37 1077
1 year 0.00 7.28 [6.41, 8.25] <1e-100 798

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_GALLBILPANC – Disorders of gallbladder, biliary tract and pancreas
GWS hits: 35

Survival analyses between endpoints

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Plot

before Disorders of gallbladder, biliary tract and pancreas
after Disorders of gallbladder, biliary tract and pancreas

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of gallbladder, biliary tract and pancreas

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