Other diseases of pancreas

K11_PANCOTH

pancreas disease: A non-neoplastic or neoplastic disorder that affects the pancreas. Representative examples of non-neoplastic disorders include pancreatitis and pancreatic insufficiency. Representative examples of neoplastic disorders include cystadenomas, carcinomas, lymphomas, and neuroendocrine neoplasms. [ NCIT:C26842 ]

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K86.2, K86.3, K86.8, K86.9

Hospital discharge: ICD-9 577[2-9]

Hospital discharge: ICD-8 5779

Cause of death: ICD-10 K86.2, K86.3, K86.8, K86.9

Cause of death: ICD-9 577[2-9]

Cause of death: ICD-8 5779

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

1235

K11_PANCOTH

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other diseases of pancreas based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

1214

533

681

Unadjusted prevalence (%)

0.39

0.31

0.50

Mean age at first event (years)

57.26

58.15

56.56

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Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	6.58 [4.45, 9.73]	3.4e-21	178
15 years	0.02	3.02 [1.95, 4.65]	6.3e-7	70
5 years	0.01	5.13 [3.12, 8.46]	1.4e-10	54
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_PANCOTH – Other diseases of pancreas
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other diseases of pancreas
after Other diseases of pancreas

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Table

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Drugs most likely to be purchased after Other diseases of pancreas

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