Other diseases of pancreas

K11_PANCOTH

pancreas disease: A non-neoplastic or neoplastic disorder that affects the pancreas. Representative examples of non-neoplastic disorders include pancreatitis and pancreatic insufficiency. Representative examples of neoplastic disorders include cystadenomas, carcinomas, lymphomas, and neuroendocrine neoplasms. [ NCIT:C26842 ]

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K86.2, K86.3, K86.8, K86.9

Hospital discharge: ICD-9 577[2-9]

Hospital discharge: ICD-8 5779

Cause of death: ICD-10 K86.2, K86.3, K86.8, K86.9

Cause of death: ICD-9 577[2-9]

Cause of death: ICD-8 5779

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

1235

K11_PANCOTH

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other diseases of pancreas based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1214	533	681
Unadjusted prevalence (%)	0.39	0.31	0.50
Mean age at first event (years)	57.26	58.15	56.56

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	6.58 [4.45, 9.73]	3.4e-21	178
15 years	0.02	3.02 [1.95, 4.65]	6.3e-7	70
5 years	0.01	5.13 [3.12, 8.46]	1.4e-10	54
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_PANCOTH – Other diseases of pancreas
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other diseases of pancreas
after Other diseases of pancreas

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Table

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Drugs most likely to be purchased after Other diseases of pancreas

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