Chronic pancreatitis

K11_CHRONPANC

alcoholic pancreatitis: Acute or chronic inflammation of the pancreas due to excessive alcohol drinking. Alcoholic pancreatitis usually presents as an acute episode but it is a chronic progressive disease in alcoholics.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K86.00, K86.01, K86.08, K86.1

Hospital discharge: ICD-9 5771

Hospital discharge: ICD-8 5771

Cause of death: ICD-10 K86.00, K86.01, K86.08, K86.1

Cause of death: ICD-9 5771

Cause of death: ICD-8 5771

KELA reimbursements: KELA codes 133

2721

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2721

Check minimum number of events None

2721

Include endpoints None

2721

K11_CHRONPANC

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Chronic pancreatitis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Alcohol-induced chronic pancreatitis

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2659	887	1772
Unadjusted prevalence (%)	0.86	0.51	1.31
Mean age at first event (years)	54.85	55.46	54.54

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	4.13 [2.66, 6.41]	2.4e-10	487
15 years	0.01	1.91 [1.27, 2.87]	1.8e-3	163
5 years	0.01	4.93 [3.61, 6.75]	1.8e-23	126
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_CHRONPANC – Chronic pancreatitis
GWS hits: 2

Survival analyses between endpoints

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Plot

before Chronic pancreatitis
after Chronic pancreatitis

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Table

Loading survival analyses table

Drugs most likely to be purchased after Chronic pancreatitis

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