Acute pancreatitis

K11_ACUTPANC

acute pancreatitis: An acute inflammatory process that leads to necrosis of the pancreatic parenchyma. Signs and symptoms include severe abdominal pain, nausea, vomiting, diarrhea, fever, and shock. Causes include alcohol consumption, presence of gallstones, trauma, and drugs.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K85

Hospital discharge: ICD-9 5770

Hospital discharge: ICD-8 5770

Cause of death: ICD-10 K85

Cause of death: ICD-9 5770

Cause of death: ICD-8 5770

4774

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

4774

Check minimum number of events None

4774

Include endpoints None

4774

K11_ACUTPANC

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 K80-K87

Name in latin Pancreatitis acuta

Similar endpoints

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List of similar endpoints to Acute pancreatitis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4648	1828	2820
Unadjusted prevalence (%)	1.51	1.05	2.09
Mean age at first event (years)	52.74	51.30	53.66

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.42 [1.90, 3.09]	9.2e-13	818
15 years	0.01	1.36 [1.09, 1.68]	5.7e-3	323
5 years	0.00	2.62 [2.13, 3.22]	6.2e-20	189
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_ACUTPANC – Acute pancreatitis
GWS hits: 6

Survival analyses between endpoints

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Plot

before Acute pancreatitis
after Acute pancreatitis

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Table

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Drugs most likely to be purchased after Acute pancreatitis

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