Acohol-induced acute pancreatitis

ALCOPANCACU

alcoholic pancreatitis: Acute or chronic inflammation of the pancreas due to excessive alcohol drinking. Alcoholic pancreatitis usually presents as an acute episode but it is a chronic progressive disease in alcoholics.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K85.2

Hospital discharge: ICD-9 5770D|5770E

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 K85.2

Cause of death: ICD-9 5770D|5770E

Cause of death: ICD-8 $!$

720

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

720

Check minimum number of events None

720

Include endpoints None

720

ALCOPANCACU

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Parent code in ICD-10 K85

Similar endpoints

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List of similar endpoints to Acohol-induced acute pancreatitis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	705	133	572
Unadjusted prevalence (%)	0.23	0.08	0.42
Mean age at first event (years)	47.46	45.99	47.81

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.80 [1.63, 4.80]	2.0e-4	124
15 years	0.01	2.12 [1.29, 3.46]	2.8e-3	56
5 years	0.00	2.53 [1.38, 4.63]	2.6e-3	16
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ALCOPANCACU – Acohol-induced acute pancreatitis
GWS hits: 2

Survival analyses between endpoints

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Plot

before Acohol-induced acute pancreatitis
after Acohol-induced acute pancreatitis

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Table

Loading survival analyses table

Drugs most likely to be purchased after Acohol-induced acute pancreatitis

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