Crohn disease (strict definition, all UC cases excluded)

K11_CD_NOUC

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions

K11_KELAIBD
and not K11_ULCER

1348

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Filter registries

Hospital Discharge: ICD-10 K50
Hospital discharge: ICD-9 555
Hospital discharge: ICD-8 5630
Cause of death: ICD-10 K50
Cause of death: ICD-9 555
Cause of death: ICD-8 5630

1048

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1048

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Check minimum number of events None

1048

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Include endpoints None

1048

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K11_CD_NOUC

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3
Parent code in ICD-10 K50-K52
Name in latin Morbus Crohn

Summary Statistics

Key figures

All Female Male
?
Number of individuals
1021 576 445
?
Unadjusted prevalence (%)
0.33 0.33 0.33
?
Mean age at first event (years)
40.92 40.07 42.03

?
Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.39 [0.61, 3.19] 4.3e-1 24
15 years 0.01 0.94 [0.38, 2.33] 8.9e-1 12
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_CD_NOUC – Crohn disease (strict definition, all UC cases excluded)
GWS hits: 3

Survival analyses between endpoints

Plot

before Crohn disease (strict definition, all UC cases excluded)
after Crohn disease (strict definition, all UC cases excluded)

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Drugs most likely to be purchased after Crohn disease (strict definition, all UC cases excluded)