Conduction disorders

DOID MESH PheWeb

I9_CONDUCTIO

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I44, I45

Hospital discharge: ICD-9 426

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 I44, I45

Cause of death: ICD-9 426

Cause of death: ICD-8 $!$

7522

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

7498

Check minimum number of events None

7498

Include endpoints

I9_AVBLOCK

I9_LBBB

I9_RBBB

7498

I9_CONDUCTIO

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Conduction disorders based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	7262	2990	4272
Unadjusted prevalence (%)	2.35	1.72	3.16
Mean age at first event (years)	64.84	61.70	67.03

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.15 [2.56, 3.87]	2.0e-27	1340
15 years	0.01	1.25 [1.00, 1.55]	5.0e-2	476
5 years	0.00	2.97 [2.48, 3.56]	4.9e-32	494
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CONDUCTIO – Conduction disorders
GWS hits: 2

Survival analyses between endpoints

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Plot

before Conduction disorders
after Conduction disorders

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Table

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Drugs most likely to be purchased after Conduction disorders

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