AV-block

I9_AVBLOCK

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 I44.0, I44.1, I44.2, I44.3
Hospital discharge: ICD-9 426[0-1]
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 I44.0, I44.1, I44.2, I44.3
Cause of death: ICD-9 426[0-1]
Cause of death: ICD-8 $!$

4125

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

4107

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Check minimum number of events None

4107

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Include endpoints None

4107

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I9_AVBLOCK

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 3968 1303 2665
Unadjusted prevalence (%) 1.29 0.75 1.97
Mean age at first event (years) 68.94 66.38 70.18

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.72 [2.82, 4.90] 1.3e-20 882
15 years 0.01 1.46 [1.14, 1.86] 2.8e-3 302
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_AVBLOCK – AV-block
GWS hits: 2

Survival analyses between endpoints

Plot

before AV-block
after AV-block

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