Operations 2 for CAVS

PheWeb

I9_CAVS_OPERATIONS2

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions

I9_CAVS_DX

7073

Filter registries

Hospital Discharge: ICD-10 I35.0, I35.2

Hospital discharge: ICD-9 4241[BC]

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 I35.0, I35.2

Cause of death: ICD-9 4241[BC]

Cause of death: ICD-8 $!$

Operations: NOMESCO codes ^FMD0[0-2]|^FMD15|^FMD96|^FME05|^FME[123467]0

7073

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

7073

Check minimum number of events None

7073

Include endpoints None

7073

I9_CAVS_OPERATIONS2

Extra metadata

First used in FinnGen datafreeze DF7

Similar endpoints

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List of similar endpoints to Operations 2 for CAVS based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Calcific aortic valvular stenosis, diagnosis (helper)

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	6860	2628	4232
Unadjusted prevalence (%)	2.22	1.51	3.13
Mean age at first event (years)	70.51	71.83	69.69

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.00 [2.33, 3.87]	2.1e-17	1680
15 years	0.01	1.36 [1.05, 1.75]	1.8e-2	631
5 years	0.00	3.00 [2.52, 3.56]	4.5e-36	564
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CAVS_OPERATIONS2 – Operations 2 for CAVS
GWS hits:

Survival analyses between endpoints

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Plot

before Operations 2 for CAVS
after Operations 2 for CAVS

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Operations 2 for CAVS

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