Calcific aortic valvular stenosis, diagnosis (helper)

I9_CAVS_DX

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 I35.0, I35.2
Hospital discharge: ICD-9 4241[BC]
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 I35.0, I35.2
Cause of death: ICD-9 4241[BC]
Cause of death: ICD-8 $!$

7073

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

7073

diagram downward connector

Check minimum number of events None

7073

diagram downward connector

Include endpoints None

7073

diagram downward connector
I9_CAVS_DX

Extra metadata

First used in FinnGen datafreeze DF6v3

Summary Statistics

Key figures

All Female Male
Number of individuals 6860 2628 4232
Unadjusted prevalence (%) 2.22 1.51 3.13
Mean age at first event (years) 70.54 71.85 69.72

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.89 [3.12, 4.85] 2.9e-33 1680
15 years 0.01 1.74 [1.44, 2.11] 1.2e-8 628
5 years 0.00 3.48 [2.97, 4.07] 5.8e-55 566
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CAVS_DX – Calcific aortic valvular stenosis, diagnosis (helper)
GWS hits:

Survival analyses between endpoints

Plot

before Calcific aortic valvular stenosis, diagnosis (helper)
after Calcific aortic valvular stenosis, diagnosis (helper)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Calcific aortic valvular stenosis, diagnosis (helper)