Calcific aortic valvular stenosis, diagnosis (helper)

PheWeb

I9_CAVS_DX

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I35.0, I35.2

Hospital discharge: ICD-9 4241[BC]

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 I35.0, I35.2

Cause of death: ICD-9 4241[BC]

Cause of death: ICD-8 $!$

7073

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

7073

Check minimum number of events None

7073

Include endpoints None

7073

I9_CAVS_DX

Extra metadata

First used in FinnGen datafreeze DF6v3

Similar endpoints

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List of similar endpoints to Calcific aortic valvular stenosis, diagnosis (helper) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Operations 2 for CAVS

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	6860	2628	4232
Unadjusted prevalence (%)	2.22	1.51	3.13
Mean age at first event (years)	70.54	71.85	69.72

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.89 [3.12, 4.85]	2.9e-33	1680
15 years	0.01	1.74 [1.44, 2.11]	1.2e-8	628
5 years	0.00	3.48 [2.97, 4.07]	5.8e-55	566
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CAVS_DX – Calcific aortic valvular stenosis, diagnosis (helper)
GWS hits:

Survival analyses between endpoints

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Plot

before Calcific aortic valvular stenosis, diagnosis (helper)
after Calcific aortic valvular stenosis, diagnosis (helper)

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Table

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Drugs most likely to be purchased after Calcific aortic valvular stenosis, diagnosis (helper)

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