Calcific aortic valvular stenosis

PheWeb

I9_CAVS

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

I9_CAVS_DX

I9_CAVS_OPERATIONS1

I9_CAVS_OPERATIONS2

7083

I9_CAVS

Extra metadata

First used in FinnGen datafreeze DF6v3

Similar endpoints

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List of similar endpoints to Calcific aortic valvular stenosis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	6870	2633	4237
Unadjusted prevalence (%)	2.23	1.52	3.14
Mean age at first event (years)	70.44	71.76	69.63

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.14 [2.55, 3.86]	3.4e-27	1681
15 years	0.01	1.43 [1.19, 1.72]	1.5e-4	632
5 years	0.00	2.83 [2.41, 3.34]	4.5e-36	564
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CAVS – Calcific aortic valvular stenosis
GWS hits:

Survival analyses between endpoints

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Plot

before Calcific aortic valvular stenosis
after Calcific aortic valvular stenosis

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Table

Loading survival analyses table

Drugs most likely to be purchased after Calcific aortic valvular stenosis

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