Graves opthalmopathy

PheWeb

GRAVES_OPHT

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions

H7_LACRIMALORBITINOTH

526

Filter registries

Hospital Discharge: ICD-10 E05.0, E05.9, E05.9+G73.0, E05.9+G73.5, E05.9+H06.2, E05.9+I43.8, E05.9+M14.5

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E05.0, E05.9, E05.9+G73.0, E05.9+G73.5, E05.9+H06.2, E05.9+I43.8, E05.9+M14.5

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

512

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

512

Check minimum number of events None

512

Include endpoints None

512

GRAVES_OPHT

Extra metadata

First used in FinnGen datafreeze DF7

Similar endpoints

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List of similar endpoints to Graves opthalmopathy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Graves opthalmopathy, strict

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	494	405	89
Unadjusted prevalence (%)	0.16	0.23	0.07
Mean age at first event (years)	51.91	51.18	55.25

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.02 [1.55, 5.89]	1.2e-3	14
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: GRAVES_OPHT – Graves opthalmopathy
GWS hits:

Survival analyses between endpoints

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Plot

before Graves opthalmopathy
after Graves opthalmopathy

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Graves opthalmopathy

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