Disorders of lacrimal system and orbit in diseases classified elsewhere

H7_LACRIMALORBITINOTH

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H06*

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 H06*

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

526

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

526

Check minimum number of events None

526

Include endpoints None

526

H7_LACRIMALORBITINOTH

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Disorders of lacrimal system and orbit in diseases classified elsewhere based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

508

416

Unadjusted prevalence (%)

0.16

0.24

0.07

Mean age at first event (years)

52.78

52.12

55.74

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Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.77 [0.31, 1.91]	5.8e-1	15
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_LACRIMALORBITINOTH – Disorders of lacrimal system and orbit in diseases classified elsewhere
GWS hits: 0

Survival analyses between endpoints

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Plot

before Disorders of lacrimal system and orbit in diseases classified elsewhere
after Disorders of lacrimal system and orbit in diseases classified elsewhere

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Table

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Drugs most likely to be purchased after Disorders of lacrimal system and orbit in diseases classified elsewhere

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