Disorders of orbit

DOID MESH PheWeb

H7_ORBIT

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H05, H06*

Cause of death: ICD-10 H05, H06*

877

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

877

Check minimum number of events None

877

Include endpoints

H7_ORBITINFLAMACU

H7_ORBITINFLAMCHRON

H7_INFLAMORBOTHICD8

H7_EXOPTHALMUS

H7_ORBITDEFORM

H7_ENOPHTHALMOS

H7_RETAINEDBODY

H7_ORBITNAS

H7_LACRIMALORBITINOTH

940

H7_ORBIT

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Disorders of orbit based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

911

641

270

Unadjusted prevalence (%)

0.30

0.37

0.20

Mean age at first event (years)

50.88

50.53

51.73

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	4.45 [3.07, 6.44]	2.7e-15	65
15 years	0.01	1.81 [1.16, 2.82]	8.9e-3	24
5 years	0.00	4.59 [2.83, 7.45]	6.8e-10	23
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_ORBIT – Disorders of orbit
GWS hits: 0

Survival analyses between endpoints

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Plot

before Disorders of orbit
after Disorders of orbit

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Table

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Drugs most likely to be purchased after Disorders of orbit

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